Concept of introducing useful agents through the manipulation of biosystems and its associated fields to Pharmacy students. Advanced concepts and application of biotechnology and its techniques. Topics involved deal with cloning, recombinant DNA (rDNA), Genetic engineering and protein production, tissue culture (plants and animals). Moreover, many techniques related to DNA will be discussed such as isolation and purification, gene splicing, enzyme systems, types of mutation and techniques related to DNA hybridization and mutation detection, Finger printing, polymerase Chain Reaction PCR, Enzyme linked immuno sorbent assay ELISA, Capillary electrophoresis CE, mutation detection methods and its correction, the management and treatment of DNA errors, and Gene therapy. DNA as a receptor and target for drug action as part of Drug Discovery will be covered.